The influence of low temperature proton irradiation on the transport property of high Tc oxide Y-Ba-Cu-O and La-Sr-Cu-O is studied by a standard four probe method. After irradiation, besides the resistivity of the sample increases and the superconducting transition temperature Tc decreases, the dp/dT of the sample increases and a metal-nonmetal phase trasition occurs. A strong annealing effect is found during warming up irradiated samples to room temperature. After room temperature annealing, nearly 60% of changes of the sample resistance and Tc which were caused by low temperature proton irradiation can be recovered. These phenomena can be attributed to that the electronic band structure of the high Tc oxide superconductor is very sensitive to the random defects.